Leptin
Wednesday, March 12th, 2008You may recall news stories from the mid-1990s that suggested that a cure for obesity had been found. The newly discovered hormone leptin was the momentary superstar because it caused obese laboratory mice to lose weight rapidly. Rodent biology being much different from human biology, the experiments turned up little of value to millions of people looking for a quick way to lose weight, and to the industry hoping to profit by selling it in a pill. Despite this misleading experiment, we do have an understanding of how leptin works in human beings, how genes influence it, and how we can make it work in sync with our weight-loss goals.
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